HI_1287 protein (Haemophilus influenzae) - STRING interaction network

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HI_1287

Type I modification enzyme (hsdM); Methylation of specific adenine residues; required for both restriction and modification activities. (443 aa)

Predicted Functional Partners:

HI_1286

0.996

HI_0216

0.970

HI_1285

0.969

HI_1650

0.726

uvrB

0.558

HI_0096

0.498

HI_0223

0.498

cmk2

0.482

Your Current Organism:

Haemophilus influenzae

NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HI_0096	HI_0223	HI_0096	HI_0223	Predicted coding region HI0096; Hypothetical protein; identified by GeneMark; putative.	rarD protein, putative; Similar to SP:P27844 percent identity: 25.08; identified by sequence similarity; putative.	0.498
HI_0096	HI_1287	HI_0096	HI_1287	Predicted coding region HI0096; Hypothetical protein; identified by GeneMark; putative.	Type I modification enzyme (hsdM); Methylation of specific adenine residues; required for both restriction and modification activities.	0.498
HI_0096	cmk2	HI_0096	HI_1646	Predicted coding region HI0096; Hypothetical protein; identified by GeneMark; putative.	Cytidylate kinase 2 (cmkB); Similar to SP:P23863 PID:42839 GB:U00096 PID:1651431 PID:1651438 percent identity: 63.55; identified by sequence similarity; putative.	0.504
HI_0216	HI_1285	HI_0216	HI_1285	Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).	Type I restriction enzyme (hsdR); Subunit R is required for both nuclease and ATPase activities, but not for modification.	0.684
HI_0216	HI_1286	HI_0216	HI_1286	Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).	Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).	0.476
HI_0216	HI_1287	HI_0216	HI_1287	Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).	Type I modification enzyme (hsdM); Methylation of specific adenine residues; required for both restriction and modification activities.	0.970
HI_0216	HI_1650	HI_0216	HI_1650	Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).	Predicted coding region HI1650; Hypothetical protein; identified by GeneMark; putative.	0.474
HI_0216	uvrB	HI_0216	HI_1247	Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).	Excinuclease ABC, subunit B (uvrB); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dis [...]	0.540
HI_0223	HI_0096	HI_0223	HI_0096	rarD protein, putative; Similar to SP:P27844 percent identity: 25.08; identified by sequence similarity; putative.	Predicted coding region HI0096; Hypothetical protein; identified by GeneMark; putative.	0.498
HI_0223	HI_1287	HI_0223	HI_1287	rarD protein, putative; Similar to SP:P27844 percent identity: 25.08; identified by sequence similarity; putative.	Type I modification enzyme (hsdM); Methylation of specific adenine residues; required for both restriction and modification activities.	0.498
HI_0223	cmk2	HI_0223	HI_1646	rarD protein, putative; Similar to SP:P27844 percent identity: 25.08; identified by sequence similarity; putative.	Cytidylate kinase 2 (cmkB); Similar to SP:P23863 PID:42839 GB:U00096 PID:1651431 PID:1651438 percent identity: 63.55; identified by sequence similarity; putative.	0.482
HI_1285	HI_0216	HI_1285	HI_0216	Type I restriction enzyme (hsdR); Subunit R is required for both nuclease and ATPase activities, but not for modification.	Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).	0.684
HI_1285	HI_1286	HI_1285	HI_1286	Type I restriction enzyme (hsdR); Subunit R is required for both nuclease and ATPase activities, but not for modification.	Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).	0.940
HI_1285	HI_1287	HI_1285	HI_1287	Type I restriction enzyme (hsdR); Subunit R is required for both nuclease and ATPase activities, but not for modification.	Type I modification enzyme (hsdM); Methylation of specific adenine residues; required for both restriction and modification activities.	0.969
HI_1286	HI_0216	HI_1286	HI_0216	Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).	Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).	0.476
HI_1286	HI_1285	HI_1286	HI_1285	Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).	Type I restriction enzyme (hsdR); Subunit R is required for both nuclease and ATPase activities, but not for modification.	0.940
HI_1286	HI_1287	HI_1286	HI_1287	Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).	Type I modification enzyme (hsdM); Methylation of specific adenine residues; required for both restriction and modification activities.	0.996
HI_1286	HI_1650	HI_1286	HI_1650	Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).	Predicted coding region HI1650; Hypothetical protein; identified by GeneMark; putative.	0.474
HI_1287	HI_0096	HI_1287	HI_0096	Type I modification enzyme (hsdM); Methylation of specific adenine residues; required for both restriction and modification activities.	Predicted coding region HI0096; Hypothetical protein; identified by GeneMark; putative.	0.498
HI_1287	HI_0216	HI_1287	HI_0216	Type I modification enzyme (hsdM); Methylation of specific adenine residues; required for both restriction and modification activities.	Type I restriction/modification specificity protein (hsdS); The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).	0.970

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