Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
csdnifS protein, putative; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (437 aa)    
Predicted Functional Partners:
HI_1293
Conserved hypothetical protein; Similar to PID:882706 GB:U00096 SP:Q46926 PID:1789176 percent identity: 36.89; identified by sequence similarity; putative; Belongs to the SufE family.
 
 0.971
iscU
iscU protein (iscU); A scaffold on which IscS assembles Fe-S clusters. Subsequently gives the nascent cluster to other proteins. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters (By similarity).
  
 0.930
HI_1296
Nuclease, putative; Similar to SP:P29769 percent identity: 46.62; identified by sequence similarity; putative; Belongs to the thermonuclease family.
       0.784
HI_1292
Predicted coding region HI1292; Hypothetical protein; identified by GeneMark; putative.
       0.773
HI_1297
Conserved hypothetical protein; Similar to SP:P33372 PID:405872 GB:U00096 PID:1788463 percent identity: 41.18; identified by sequence similarity; putative.
       0.548
trxB
Thioredoxin reductase (trxB); Similar to GB:J03762 SP:P09625 PID:148073 PID:347239 GB:U00096 percent identity: 75.95; identified by sequence similarity; putative.
  
 
  0.535
HI_1298
Conserved hypothetical transmembrane protein; Similar to SP:P33373 PID:405873 GB:U00096 PID:1788464 percent identity: 43.52; identified by sequence similarity; putative.
       0.513
queF
Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
       0.506
moeA
Molybdopterin biosynthesis protein (moeA); Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP; Belongs to the MoeA family.
    
 0.436
selD
Selenide, water dikinase (selD); Synthesizes selenophosphate from selenide and ATP.
    
  0.435
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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