Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
canCarbonic anhydrase, putative; Similar to PID:1513236 percent identity: 57.55; identified by sequence similarity; putative; Belongs to the beta-class carbonic anhydrase family. (229 aa)    
Predicted Functional Partners:
focA
Formate transporter; Involved in the bidirectional transport of formate. Belongs to the FNT transporter (TC 2.A.44) family.
  
    0.712
asnS
asparaginyl-tRNA synthetase (asnS); Similar to GB:M33145 SP:P17242 GB:X68192 PID:147935 PID:41000 percent identity: 80.65; identified by sequence similarity; putative.
  
    0.643
ribH
Riboflavin synthase, beta chain (ribH); Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.
       0.437
nusB
N utilization substance protein B (nusB); Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
       0.437
guaB
Inosine-5'-monophosphate dehydrogenase (guaB); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 
 0.430
zapA
Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity).
      
 0.418
gpt1
Xanthine-guanine phosphoribosyltransferase (gptA); Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
   
    0.401
HI_0692
Xanthine-guanine phosphoribosyltransferase (gptB); Similar to SP:P26972 GB:X52093 GB:X63336 PID:47695 percent identity: 74.03; identified by sequence similarity; putative.
   
    0.401
apt
Adenine phosphoribosyltransferase (apt); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.401
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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