STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HI_1317Conserved hypothetical protein; Similar to GB:U00096 SP:P39173 PID:1736408 PID:1742898 PID:1788080 percent identity: 39.01; identified by sequence similarity; putative. (271 aa)    
Predicted Functional Partners:
tktA
Transketolase 1 (tktA); Catalyzes the reversible transfer of a two-carbon ketol group from sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate, producing xylulose-5-phosphate and ribose-5-phosphate. Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate (By similarity).
     
 0.679
deoC
Deoxyribose-phosphate aldolase (deoC); Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
     
 0.662
pgi
Glucose-6-phosphate isomerase (pgi); Similar to SP:P11537 GB:X15196 PID:396360 PID:42377 GB:U00096 percent identity: 77.05; identified by sequence similarity; putative.
   
 
 0.636
fba
Fructose-bisphosphate aldolase (fba); Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
   
 
 0.634
zwf
Glucose-6-phosphate 1-dehydrogenase (zwf); Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
  
  0.630
eda
4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-deoxyphosphogluconate aldolase (eda); Similar to GB:L20897 GB:M87458 GB:X63694 GB:X68871 PID:145827 percent identity: 37.31; identified by sequence similarity; putative; Belongs to the KHG/KDPG aldolase family.
    
  0.578
HI_1316
Predicted coding region HI1316; Hypothetical protein; identified by GeneMark; putative.
       0.560
tal
Transaldolase B (talB); Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
   
 
  0.559
denD
Conserved hypothetical protein; Catalyzes oxidation of D-erythronate to 2-oxo-tetronate. Can use either NAD(+) or NADP(+) as cosubstrate, with a preference for NAD(+).
     
 0.495
infC
Translation initiation factor 3 (infC); IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
       0.416
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.