Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HI_0387 | dnaN | HI_0387 | HI_0992 | ATP-dependent helicase (dinG); Similar to GB:U00096 PID:1736441 PID:1736447 PID:1788110 percent identity: 61.17; identified by sequence similarity; putative; Belongs to the helicase family. DinG subfamily. | DNA polymerase III, beta subunit (dnaN); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...] | 0.792 |
| HI_0387 | polA | HI_0387 | HI_0856 | ATP-dependent helicase (dinG); Similar to GB:U00096 PID:1736441 PID:1736447 PID:1788110 percent identity: 61.17; identified by sequence similarity; putative; Belongs to the helicase family. DinG subfamily. | DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | 0.909 |
| HI_0387 | recA | HI_0387 | HI_0600 | ATP-dependent helicase (dinG); Similar to GB:U00096 PID:1736441 PID:1736447 PID:1788110 percent identity: 61.17; identified by sequence similarity; putative; Belongs to the helicase family. DinG subfamily. | recA protein (recA); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage. Plays a central role in DNA metabolism, participating in general homologous recombination, recombinational (postreplication) DNA repair, and prophage induction; Belongs to the RecA family. | 0.677 |
| HI_0387 | recD | HI_0387 | HI_1322 | ATP-dependent helicase (dinG); Similar to GB:U00096 PID:1736441 PID:1736447 PID:1788110 percent identity: 61.17; identified by sequence similarity; putative; Belongs to the helicase family. DinG subfamily. | Exodeoxyribonuclease V, alpha chain (recD); A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination [...] | 0.570 |
| HI_0387 | recQ | HI_0387 | HI_0728 | ATP-dependent helicase (dinG); Similar to GB:U00096 PID:1736441 PID:1736447 PID:1788110 percent identity: 61.17; identified by sequence similarity; putative; Belongs to the helicase family. DinG subfamily. | ATP-dependent DNA helicase (recQ); DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.717 |
| HI_0387 | topA | HI_0387 | HI_1365 | ATP-dependent helicase (dinG); Similar to GB:U00096 PID:1736441 PID:1736447 PID:1788110 percent identity: 61.17; identified by sequence similarity; putative; Belongs to the helicase family. DinG subfamily. | DNA topoisomerase I (topA); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing D [...] | 0.681 |
| HI_0387 | truB | HI_0387 | HI_1289 | ATP-dependent helicase (dinG); Similar to GB:U00096 PID:1736441 PID:1736447 PID:1788110 percent identity: 61.17; identified by sequence similarity; putative; Belongs to the helicase family. DinG subfamily. | tRNA pseudouridine 55 synthase (truB); Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.559 |
| HI_0387 | uvrD | HI_0387 | HI_1188 | ATP-dependent helicase (dinG); Similar to GB:U00096 PID:1736441 PID:1736447 PID:1788110 percent identity: 61.17; identified by sequence similarity; putative; Belongs to the helicase family. DinG subfamily. | DNA helicase II (uvrD); May process damage occurring in non-replicating regions of DNA to produce recombinational intermediates for sister strand recombinational exchange. | 0.406 |
| dnaN | HI_0387 | HI_0992 | HI_0387 | DNA polymerase III, beta subunit (dnaN); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...] | ATP-dependent helicase (dinG); Similar to GB:U00096 PID:1736441 PID:1736447 PID:1788110 percent identity: 61.17; identified by sequence similarity; putative; Belongs to the helicase family. DinG subfamily. | 0.792 |
| dnaN | polA | HI_0992 | HI_0856 | DNA polymerase III, beta subunit (dnaN); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...] | DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | 0.999 |
| dnaN | recA | HI_0992 | HI_0600 | DNA polymerase III, beta subunit (dnaN); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...] | recA protein (recA); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage. Plays a central role in DNA metabolism, participating in general homologous recombination, recombinational (postreplication) DNA repair, and prophage induction; Belongs to the RecA family. | 0.885 |
| dnaN | recD | HI_0992 | HI_1322 | DNA polymerase III, beta subunit (dnaN); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...] | Exodeoxyribonuclease V, alpha chain (recD); A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination [...] | 0.793 |
| dnaN | recQ | HI_0992 | HI_0728 | DNA polymerase III, beta subunit (dnaN); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...] | ATP-dependent DNA helicase (recQ); DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.821 |
| dnaN | topA | HI_0992 | HI_1365 | DNA polymerase III, beta subunit (dnaN); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...] | DNA topoisomerase I (topA); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing D [...] | 0.691 |
| dnaN | uvrD | HI_0992 | HI_1188 | DNA polymerase III, beta subunit (dnaN); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...] | DNA helicase II (uvrD); May process damage occurring in non-replicating regions of DNA to produce recombinational intermediates for sister strand recombinational exchange. | 0.825 |
| polA | HI_0387 | HI_0856 | HI_0387 | DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | ATP-dependent helicase (dinG); Similar to GB:U00096 PID:1736441 PID:1736447 PID:1788110 percent identity: 61.17; identified by sequence similarity; putative; Belongs to the helicase family. DinG subfamily. | 0.909 |
| polA | dnaN | HI_0856 | HI_0992 | DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | DNA polymerase III, beta subunit (dnaN); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...] | 0.999 |
| polA | recA | HI_0856 | HI_0600 | DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | recA protein (recA); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage. Plays a central role in DNA metabolism, participating in general homologous recombination, recombinational (postreplication) DNA repair, and prophage induction; Belongs to the RecA family. | 0.999 |
| polA | recB | HI_0856 | HI_1321 | DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | Exodeoxyribonuclease V, beta chain (recB); A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination a [...] | 0.670 |
| polA | recC | HI_0856 | HI_0942 | DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | Exodeoxyribonuclease V, gamma chain (recC); A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination [...] | 0.493 |
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