Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glgB1,4-alpha-glucan branching enzyme (glgB); Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (730 aa)    
Predicted Functional Partners:
malQ
4-alpha-glucanotransferase (malQ); Similar to GB:M32793 SP:P15977 PID:146715 PID:606351 GB:U00096 percent identity: 41.59; identified by sequence similarity; putative; Belongs to the disproportionating enzyme family.
 
 0.999
glgA
Glycogen synthase (glgA); Synthesizes alpha-1,4-glucan chains using ADP-glucose.
 
 0.999
glgX
Glycogen operon protein (glgX); Similar to GB:J01616 SP:P15067 PID:146135 PID:606366 GB:U00096 percent identity: 52.77; identified by sequence similarity; putative; Belongs to the glycosyl hydrolase 13 family.
 
 
0.998
glgC
Glucose-1-phosphate adenylyltransferase (glgC); Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
 
 
 0.997
glgP
Glycogen phosphorylase (glgP); Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity).
 
 0.997
HI_1698
Lipopolysaccharide biosynthesis protein; Similar to PID:633695 percent identity: 38.48; identified by sequence similarity; putative.
   
 0.946
atpD
ATP synthase F1, subunit beta (atpD); Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.
    
 0.704
HI_1355
Conserved hypothetical protein; Similar to GB:U00096 PID:1787429 percent identity: 45.70; identified by sequence similarity; putative; Belongs to the UPF0260 family.
       0.580
galU
Glucosephosphate uridylyltransferase (galU); May play a role in stationary phase survival; Belongs to the UDPGP type 2 family.
  
 
 0.530
birA
Biotin operon repressor/biotin acetyl coenzyme A carboxylase synthetase (birA); Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
      
 0.469
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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