Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
HI_1370Molybdenum-pterin binding protein (mopI); Binds one mole of molybdenum per mole of protein and contains a pterin. (69 aa)    
Predicted Functional Partners:
HI_1369
Conserved hypothetical protein; Similar to SP:P31827 GB:X71917 PID:311346 GB:U00096 PID:1787771 percent identity: 25.46; identified by sequence similarity; putative; To E.coli YddB.
       0.636
HI_1268
Predicted coding region HI1268; Hypothetical protein; identified by GeneMark; putative.
 
     0.627
modE
Molybdenum transport protein (modE); The ModE-Mo complex acts as a repressor of the modABC operon, involved in the transport of molybdate. Upon binding molybdate, the conformation of the protein changes, promoting dimerization of ModE-Mo. The protein dimer is then competent to bind a DNA region, upstream of the modABC operon. Acts also as an enhancer of the expression of genes coding for molybdoenzymes, both directly and indirectly (By similarity).
 
 
   0.532
tusE
Desulfoviridin gamma subunit, putative; Could be part of a sulfur-relay system; Belongs to the DsrC/TusE family.
       0.518
ttcA
Conserved hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
       0.518
modC
Molybdenum ABC transporter, ATP-binding protein (modC); Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
   
 0.503
modB
Molybdenum ABC transporter, permease protein (modB); Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
    
 0.485
HI_1525
Molybdate-binding periplasmic protein, putative; Probably involved in the binding-dependent system; Belongs to the bacterial solute-binding protein ModA family.
 
  
 0.483
pqqL
Zinc protease, putative; Similar to SP:P31828 GB:X71917 PID:535004 GB:U00096 PID:1742451 percent identity: 28.76; identified by sequence similarity; putative.
       0.440
modA
Molybdenum ABC transporter, periplasmic-binding protein (modA); Involved in the transport of molybdenum into the cell.
 
  
 0.437
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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