Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HI_1395Predicted coding region HI1395; Hypothetical protein; identified by GeneMark; putative. (140 aa)    
Predicted Functional Partners:
HI_1396
Predicted coding region HI1396; Hypothetical protein; identified by GeneMark; putative.
       0.773
HI_1458
Predicted coding region HI1458; Hypothetical protein; identified by GeneMark; putative.
    
 
 0.698
holC
DNA polymerase III, chi subunit (holC); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity).
       0.550
valS
valyl-tRNA synthetase (valS); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
       0.452
hindIIIM
Modification methylase (hindIIIM); This methylase recognizes the double-stranded sequence AAGCTT, causes specific methylation on A-1 on both strands, and protects the DNA from cleavage by the HindIII endonuclease; Belongs to the N(4)/N(6)-methyltransferase family.
       0.434
hindIIIR
Type II restriction endonuclease (hindIIIR); Recognizes the double-stranded sequence AAGCTT and cleaves after A-1.
       0.434
HI_1394
Conserved hypothetical protein; Similar to PID:887850 GB:U00096 SP:Q46828 PID:1789267 percent identity: 68.32; identified by sequence similarity; putative; Belongs to the UPF0267 family.
       0.434
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.