Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
usgUsg-1 protein (usg1); Similar to SP:P08390 GB:X02743 PID:147125 PID:41717 GB:U00096 percent identity: 32.71; identified by sequence similarity; putative; Belongs to the aspartate-semialdehyde dehydrogenase family. (317 aa)    
Predicted Functional Partners:
thrA
Aspartokinase I / homoserine dehydrogenase I (thrA); Similar to SP:P00561 GB:M10644 GB:V00360 GB:V00361 PID:147979 percent identity: 62.21; identified by sequence similarity; putative; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 0.969
dapA
Dihydrodipicolinate synthetase (dapA); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
 
 0.778
HI_1632
Predicted coding region HI1632; Hypothetical protein; identified by GeneMark; putative; Belongs to the aspartokinase family.
  
 
 0.715
ybaK
Transcriptional regulator, putative; Functions in trans to edit the amino acid from incorrectly charged Cys-tRNA(Pro) via a Cys-tRNA(Pro) deacylase activity. Probably compensates for the lack of Cys-tRNA(Pro) editing by ProRS. Is also able to deacylate Cys-tRNA(Cys), and displays weak deacylase activity in vitro against Gly-tRNA(Gly), as well as, at higher concentrations, some other correctly charged tRNAs. Does not cleave Pro-tRNA(Pro). Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.
       0.566
bioA
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (bioA); Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
    
 0.536
pgk
Phosphoglycerate kinase (pgk); Similar to SP:P11665 PID:41422 PID:882455 GB:U00096 PID:1789294 percent identity: 81.14; identified by sequence similarity; putative; Belongs to the phosphoglycerate kinase family.
  
  0.528
dat
Aminotransferase; Similar to PID:2340815 percent identity: 71.85; identified by sequence similarity; putative.
     
 0.522
nanA
N-acetylneuraminate lyase (nanA); Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate; Belongs to the DapA family. NanA subfamily.
  
 
 0.492
ilvH
Acetolactate synthase III small subunit (ilvH); Similar to GB:D10483 SP:P00894 GB:X01609 PID:216495 PID:40846 percent identity: 65.62; identified by sequence similarity; putative; Belongs to the acetolactate synthase small subunit family.
  
 
 0.469
lysA
Diaminopimelate decarboxylase (lysA); Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 
 0.457
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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