Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
HI_1462Conserved hypothetical protein; Similar to GB:U00096 SP:P77211 PID:1778487 PID:1786785 percent identity: 24.32; identified by sequence similarity; putative; Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. (454 aa)    
Predicted Functional Partners:
HI_0894
Lipoprotein, putative; Similar to GB:U14993 SP:P43505 PID:438192 PID:550460 percent identity: 30.92; identified by sequence similarity; putative.
 
 0.977
emrA
Multidrug resistance protein A (emrA); Confers resistance to antibiotics; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.949
HI_0895
Acriflavine resistance protein (acrB); Could be a drug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 0.928
HI_1466.1
Predicted coding region HI1466.1; Brute Force ORF; identified by GeneMark; putative; Belongs to the TonB-dependent receptor family.
  
   0.604
HI_1466
Predicted coding region HI1466; Hypothetical protein; identified by GeneMark; putative.
  
   0.550
emrB
Multidrug resistance protein B (emrB); Confers resistance to antibiotics; Belongs to the major facilitator superfamily. EmrB family.
 
 
 0.549
hsrA
Conserved hypothetical transmembrane protein; Similar to GB:L10328 SP:P31474 PID:290604 GB:U00096 PID:1790195 percent identity: 44.91; identified by sequence similarity; putative.
 
 
 0.547
HI_0974
Predicted coding region HI0974; Hypothetical protein; identified by GeneMark; putative.
  
     0.507
HI_1405
Predicted coding region HI1405; Hypothetical protein; identified by GeneMark; putative.
  
     0.467
pal
Peptidoglycan-associated outer membrane lipoprotein (pal); Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 0.462
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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