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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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HI_1564Predicted coding region HI1564; Hypothetical protein; identified by GeneMark; putative. (50 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta subunit (dnaN); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...]
   
 0.949
polA
DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.
  
 0.758
recA
recA protein (recA); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage. Plays a central role in DNA metabolism, participating in general homologous recombination, recombinational (postreplication) DNA repair, and prophage induction; Belongs to the RecA family.
  
 0.757
holB
DNA polymerase III, delta' subunit (holB); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity).
  
 
 0.756
epmC
Conserved hypothetical protein; Is involved in the final hydroxylation step of the post- translational modification of translation elongation factor P (EF-P) on 'Lys-34'. Acts after beta-lysylation of 'Lys-34' by EpmA and EpmB. EpmC adds an oxygen atom to the C5 position of 'Lys-34' and does not modify the added beta-lysine (By similarity).
       0.685
HI_1564.1
Predicted coding region HI1564.1; Hypothetical protein; identified by GeneMark; putative.
       0.671
lexA
lexA repressor (lexA); Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
 
 0.587
HI_1546
impA protein, putative; Similar to percent identity: 34.26; identified by sequence similarity; putative; Belongs to the peptidase S24 family.
  
 
 0.587
HI_0868
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 35.37; identified by sequence similarity; putative; Belongs to the glycosyltransferase 2 family.
      
 0.579
HI_0869
Predicted coding region HI0869; Hypothetical protein; identified by GeneMark; putative.
      
 0.579
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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