| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| hmrM | ribE | HI_1612 | HI_1613 | Conserved hypothetical transmembrane protein; Multidrug efflux pump that functions as a Na(+)/drug antiporter. Confers resistance to norfloxacin, acriflavine, doxorubicin, ethidium bromide, tetraphenylphosphonium chloride, daunomycin, berberine and sodium deoxycholate. Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. | Riboflavin synthase, alpha chain (ribE); Catalyzes the dismutation of two molecules of 6,7-dimethyl-8- ribityllumazine, resulting in the formation of riboflavin and 5-amino- 6-(D-ribitylamino)uracil. | 0.635 |
| hmrM | sfsA | HI_1612 | HI_1611 | Conserved hypothetical transmembrane protein; Multidrug efflux pump that functions as a Na(+)/drug antiporter. Confers resistance to norfloxacin, acriflavine, doxorubicin, ethidium bromide, tetraphenylphosphonium chloride, daunomycin, berberine and sodium deoxycholate. Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. | Sugar fermentation stimulation protein (sfsA); Similar to GB:D26562 SP:P18273 GB:M34945 GB:M60726 PID:145750 percent identity: 54.79; identified by sequence similarity; putative; Belongs to the SfsA family. | 0.773 |
| hmrM | tyrS | HI_1612 | HI_1610 | Conserved hypothetical transmembrane protein; Multidrug efflux pump that functions as a Na(+)/drug antiporter. Confers resistance to norfloxacin, acriflavine, doxorubicin, ethidium bromide, tetraphenylphosphonium chloride, daunomycin, berberine and sodium deoxycholate. Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. | Tyrosyl tRNA synthetase (tyrS); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. | 0.444 |
| proA | sfsA | HI_1239 | HI_1611 | Gamma-glutamyl phosphate reductase (proA); Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | Sugar fermentation stimulation protein (sfsA); Similar to GB:D26562 SP:P18273 GB:M34945 GB:M60726 PID:145750 percent identity: 54.79; identified by sequence similarity; putative; Belongs to the SfsA family. | 0.549 |
| ribE | hmrM | HI_1613 | HI_1612 | Riboflavin synthase, alpha chain (ribE); Catalyzes the dismutation of two molecules of 6,7-dimethyl-8- ribityllumazine, resulting in the formation of riboflavin and 5-amino- 6-(D-ribitylamino)uracil. | Conserved hypothetical transmembrane protein; Multidrug efflux pump that functions as a Na(+)/drug antiporter. Confers resistance to norfloxacin, acriflavine, doxorubicin, ethidium bromide, tetraphenylphosphonium chloride, daunomycin, berberine and sodium deoxycholate. Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. | 0.635 |
| ribE | sfsA | HI_1613 | HI_1611 | Riboflavin synthase, alpha chain (ribE); Catalyzes the dismutation of two molecules of 6,7-dimethyl-8- ribityllumazine, resulting in the formation of riboflavin and 5-amino- 6-(D-ribitylamino)uracil. | Sugar fermentation stimulation protein (sfsA); Similar to GB:D26562 SP:P18273 GB:M34945 GB:M60726 PID:145750 percent identity: 54.79; identified by sequence similarity; putative; Belongs to the SfsA family. | 0.562 |
| ribE | tyrS | HI_1613 | HI_1610 | Riboflavin synthase, alpha chain (ribE); Catalyzes the dismutation of two molecules of 6,7-dimethyl-8- ribityllumazine, resulting in the formation of riboflavin and 5-amino- 6-(D-ribitylamino)uracil. | Tyrosyl tRNA synthetase (tyrS); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. | 0.441 |
| sfsA | hmrM | HI_1611 | HI_1612 | Sugar fermentation stimulation protein (sfsA); Similar to GB:D26562 SP:P18273 GB:M34945 GB:M60726 PID:145750 percent identity: 54.79; identified by sequence similarity; putative; Belongs to the SfsA family. | Conserved hypothetical transmembrane protein; Multidrug efflux pump that functions as a Na(+)/drug antiporter. Confers resistance to norfloxacin, acriflavine, doxorubicin, ethidium bromide, tetraphenylphosphonium chloride, daunomycin, berberine and sodium deoxycholate. Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. | 0.773 |
| sfsA | proA | HI_1611 | HI_1239 | Sugar fermentation stimulation protein (sfsA); Similar to GB:D26562 SP:P18273 GB:M34945 GB:M60726 PID:145750 percent identity: 54.79; identified by sequence similarity; putative; Belongs to the SfsA family. | Gamma-glutamyl phosphate reductase (proA); Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.549 |
| sfsA | ribE | HI_1611 | HI_1613 | Sugar fermentation stimulation protein (sfsA); Similar to GB:D26562 SP:P18273 GB:M34945 GB:M60726 PID:145750 percent identity: 54.79; identified by sequence similarity; putative; Belongs to the SfsA family. | Riboflavin synthase, alpha chain (ribE); Catalyzes the dismutation of two molecules of 6,7-dimethyl-8- ribityllumazine, resulting in the formation of riboflavin and 5-amino- 6-(D-ribitylamino)uracil. | 0.562 |
| sfsA | tyrS | HI_1611 | HI_1610 | Sugar fermentation stimulation protein (sfsA); Similar to GB:D26562 SP:P18273 GB:M34945 GB:M60726 PID:145750 percent identity: 54.79; identified by sequence similarity; putative; Belongs to the SfsA family. | Tyrosyl tRNA synthetase (tyrS); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. | 0.444 |
| tyrS | hmrM | HI_1610 | HI_1612 | Tyrosyl tRNA synthetase (tyrS); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. | Conserved hypothetical transmembrane protein; Multidrug efflux pump that functions as a Na(+)/drug antiporter. Confers resistance to norfloxacin, acriflavine, doxorubicin, ethidium bromide, tetraphenylphosphonium chloride, daunomycin, berberine and sodium deoxycholate. Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. | 0.444 |
| tyrS | ribE | HI_1610 | HI_1613 | Tyrosyl tRNA synthetase (tyrS); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. | Riboflavin synthase, alpha chain (ribE); Catalyzes the dismutation of two molecules of 6,7-dimethyl-8- ribityllumazine, resulting in the formation of riboflavin and 5-amino- 6-(D-ribitylamino)uracil. | 0.441 |
| tyrS | sfsA | HI_1610 | HI_1611 | Tyrosyl tRNA synthetase (tyrS); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. | Sugar fermentation stimulation protein (sfsA); Similar to GB:D26562 SP:P18273 GB:M34945 GB:M60726 PID:145750 percent identity: 54.79; identified by sequence similarity; putative; Belongs to the SfsA family. | 0.444 |
