Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
zntRMercuric resistance operon regulatory protein (merR2); Transcriptional regulator. (135 aa)    
Predicted Functional Partners:
HI_0186
Transcriptional regulator, putative; Similar to GB:D26185 SP:P37510 PID:467364 GB:AL009126 percent identity: 43.40; identified by sequence similarity; putative.
  
   
 0.764
HI_1624
Predicted coding region HI1624; Hypothetical protein; identified by GeneMark; putative.
       0.551
HI_0290
Potassium/copper-transporting ATPase, putative; Similar to GB:AL009126 percent identity: 39.57; identified by sequence similarity; putative; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
  
  
 0.543
maeB
Malate oxidoreductase, putative; Similar to GB:U00096 PID:1788806 PID:1799885 PID:1799887 percent identity: 68.69; identified by sequence similarity; putative; In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
    
  0.540
HI_1621
Conserved hypothetical protein; May be involved in metal transport; Belongs to the CbiM family.
  
    0.540
HI_1620
Predicted coding region HI1620; Hypothetical protein; identified by GeneMark; putative.
       0.539
HI_1622
Predicted coding region HI1622; Hypothetical protein; identified by GeneMark; putative.
       0.539
rpoB
DNA-directed RNA polymerase, beta chain (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.527
glnA
Glutamine synthetase (glnA); Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family.
  
 
 0.516
queF
Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
     
  0.492
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
Server load: low (26%) [HD]