Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HI_1625Predicted coding region HI1625; Hypothetical protein; identified by GeneMark; putative. (165 aa)    
Predicted Functional Partners:
hisS
histidyl-tRNA synthetase (hisS); Similar to GB:M11843 SP:P04804 PID:146372 GB:U00096 PID:1788861 percent identity: 66.82; identified by sequence similarity; putative.
    
  0.791
HI_1626
Conserved hypothetical protein; Similar to SP:P46909 PID:971339 GB:AL009126 percent identity: 34.62; identified by sequence similarity; putative.
       0.782
htpX
Heat shock protein (htpX); Similar to GB:M58470 SP:P23894 PID:146412 GB:U00096 PID:1736470 percent identity: 66.32; identified by sequence similarity; putative; Belongs to the peptidase M48B family.
   
 
  0.703
kdkA
Predicted coding region HI0260.1; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position. To a lesser extent, can use GTP instead of ATP as substrate.
    
  0.630
dnaJ
Heat shock protein (dnaJ); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ [...]
   
 
 0.566
HI_1627
Conserved hypothetical protein; Similar to PID:2407234 percent identity: 56.64; identified by sequence similarity; putative; Belongs to the RutC family.
       0.540
qseC
Sensor protein (ygiY); Member of a two-component regulatory system QseB/QseC. May activate QseB by phosphorylation (By similarity).
    
 0.503
HI_1628
Conserved hypothetical protein; Similar to SP:P39436 PID:606172 GB:U00096 PID:1789628 percent identity: 35.94; identified by sequence similarity; putative; To E.coli YhcB.
       0.475
mdh
Malate dehydrogenase (mdh); Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 
   0.473
ompA
Outer membrane protein P5 (ompA); With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
   
 
 0.468
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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