Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HI_1658Hemolysin, putative; Similar to SP:P45467 PID:606090 GB:U00096 PID:1789540 percent identity: 51.10; identified by sequence similarity; putative. (193 aa)    
Predicted Functional Partners:
HI_1657
Conserved hypothetical protein; Similar to SP:P45466 PID:606089 GB:U00096 PID:1789539 percent identity: 35.26; identified by sequence similarity; putative; Belongs to the SIS family. DiaA subfamily.
  
    0.750
lpoA
Antigen; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).
  
    0.674
HI_1656
Conserved hypothetical protein; Similar to SP:P45465 PID:606088 GB:U00096 PID:1789538 percent identity: 48.67; identified by sequence similarity; putative; Belongs to the UPF0102 family.
       0.665
rsmI
Conserved hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
       0.528
nrdA
Ribonucleoside-diphosphate reductase, alpha chain (nrdA); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
       0.455
dacA
Penicillin-binding protein 5 (dacA); Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Belongs to the peptidase S11 family.
  
  
 0.439
bamD
Lipoprotein, putative; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
   
 0.414
ftsB
Conserved hypothetical protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
  
     0.414
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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