STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gloCConserved hypothetical protein; Type II glyoxalase, isozyme of GloB, that hydrolyzes (R)-S- lactoylglutathione to (R)-lactate and glutathione. Plays a role in methylglyoxal (MG) detoxification. (212 aa)    
Predicted Functional Partners:
HI_1665
Predicted coding region HI1665; Hypothetical protein; identified by GeneMark; putative.
  
    0.806
HI_1666
Conserved hypothetical protein; Similar to GB:U00096 SP:P75848 PID:1787157 percent identity: 49.73; identified by sequence similarity; putative.
 
    0.787
HI_1664
Conserved hypothetical protein; Similar to GB:U00089 SP:P78005 PID:1673805 percent identity: 31.05; identified by sequence similarity; putative.
       0.774
HI_1163
Conserved hypothetical protein; Similar to GB:U00096 SP:P77748 PID:1742760 PID:1787977 percent identity: 60.82; identified by sequence similarity; putative.
    
 0.720
HI_0744
Conserved hypothetical protein; Similar to SP:P37688 PID:466749 GB:U00096 PID:1790040 percent identity: 50.74; identified by sequence similarity; putative.
  
 0.676
gloB
Hydroxyacylglutathione hydrolase, putative; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
  
  
 
0.646
gloA
Lactoylglutathione lyase (gloA); Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
  
 0.645
HI_1667
Conserved hypothetical protein; Similar to SP:P22525 GB:X57550 PID:42044 GB:U00096 PID:1787155 percent identity: 42.12; identified by sequence similarity; putative; Belongs to the YkuD family.
 
     0.620
dld
D-lactate dehydrogenase (dld); Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.
  
  
 0.615
glpE
glpE protein (glpE); Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
  
 0.568
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.