Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
HI_1681Conserved hypothetical protein; Similar to GB:U00096 PID:1787198 percent identity: 26.85; identified by sequence similarity; putative; Belongs to the UPF0319 family. (221 aa)    
Predicted Functional Partners:
oapA
Opacity associated protein (oapA); Cell envelope protein involved in phase variation, confers opaque colony phenotype; Belongs to the OapA family.
  
     0.702
nrfB
Nitrite reductase, cytochrome C-type protein (nrfB); Plays a role in nitrite reduction.
  
     0.680
HI_0845
Conserved hypothetical protein; Similar to GB:L19201 SP:P32126 PID:304964 GB:U00096 PID:1790289 percent identity: 65.91; identified by sequence similarity; putative; To E.coli YihD.
  
     0.671
HI_1369
Conserved hypothetical protein; Similar to SP:P31827 GB:X71917 PID:311346 GB:U00096 PID:1787771 percent identity: 25.46; identified by sequence similarity; putative; To E.coli YddB.
  
     0.670
HI_1680
Conserved hypothetical transmembrane protein; Similar to GB:U00096 PID:1787194 percent identity: 38.90; identified by sequence similarity; putative.
 
   
 0.653
HI_1399
Predicted coding region HI1399; Hypothetical protein; identified by GeneMark; putative.
  
     0.623
HI_1624
Predicted coding region HI1624; Hypothetical protein; identified by GeneMark; putative.
  
     0.623
lapA
Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.603
tfoX
DNA transformation protein (tfoX); Required for DNA transformation. Positively regulates genes required for DNA transformation (late competence-specific genes) in association with CRP. Required for expression of the dprABC operon ; Belongs to the TfoX family.
  
     0.584
hemY
hemY protein (hemY); Involved in a late step of protoheme IX synthesis.
  
     0.566
Your Current Organism:
Haemophilus influenzae
NCBI taxonomy Id: 71421
Other names: H. influenzae Rd KW20, Haemophilus influenzae KW20, Haemophilus influenzae Rd, Haemophilus influenzae Rd KW20
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