node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OJG81759.1 | OJG84754.1 | RV13_GL002980 | RV13_GL001598 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Pyruvate oxidase; Belongs to the TPP enzyme family. | 0.921 |
OJG81759.1 | OJG86426.1 | RV13_GL002980 | RV13_GL000397 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.992 |
OJG81759.1 | OJG86444.1 | RV13_GL002980 | RV13_GL000415 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Acetolactate synthase, small subunit. | 0.908 |
OJG81759.1 | OJG86445.1 | RV13_GL002980 | RV13_GL000416 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Acetolactate synthase, large subunit, biosynthetic type. | 0.921 |
OJG81759.1 | ilvD | RV13_GL002980 | RV13_GL000417 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.577 |
OJG81759.1 | leuA | RV13_GL002980 | RV13_GL001997 | Pyruvate kinase; Belongs to the pyruvate kinase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.926 |
OJG81759.1 | leuC | RV13_GL002980 | RV13_GL001999 | Pyruvate kinase; Belongs to the pyruvate kinase family. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.921 |
OJG81759.1 | leuD | RV13_GL002980 | RV13_GL002000 | Pyruvate kinase; Belongs to the pyruvate kinase family. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.937 |
OJG84754.1 | OJG81759.1 | RV13_GL001598 | RV13_GL002980 | Pyruvate oxidase; Belongs to the TPP enzyme family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.921 |
OJG84754.1 | OJG86426.1 | RV13_GL001598 | RV13_GL000397 | Pyruvate oxidase; Belongs to the TPP enzyme family. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.966 |
OJG84754.1 | OJG86444.1 | RV13_GL001598 | RV13_GL000415 | Pyruvate oxidase; Belongs to the TPP enzyme family. | Acetolactate synthase, small subunit. | 0.996 |
OJG84754.1 | ilvC | RV13_GL001598 | RV13_GL000414 | Pyruvate oxidase; Belongs to the TPP enzyme family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.978 |
OJG84754.1 | ilvD | RV13_GL001598 | RV13_GL000417 | Pyruvate oxidase; Belongs to the TPP enzyme family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.897 |
OJG84754.1 | leuA | RV13_GL001598 | RV13_GL001997 | Pyruvate oxidase; Belongs to the TPP enzyme family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.944 |
OJG84754.1 | leuB | RV13_GL001598 | RV13_GL001998 | Pyruvate oxidase; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.948 |
OJG84754.1 | leuC | RV13_GL001598 | RV13_GL001999 | Pyruvate oxidase; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.941 |
OJG84754.1 | leuD | RV13_GL001598 | RV13_GL002000 | Pyruvate oxidase; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.946 |
OJG86426.1 | OJG81759.1 | RV13_GL000397 | RV13_GL002980 | Pyruvate:ferredoxin (flavodoxin) oxidoreductase. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.992 |
OJG86426.1 | OJG84754.1 | RV13_GL000397 | RV13_GL001598 | Pyruvate:ferredoxin (flavodoxin) oxidoreductase. | Pyruvate oxidase; Belongs to the TPP enzyme family. | 0.966 |
OJG86426.1 | OJG86444.1 | RV13_GL000397 | RV13_GL000415 | Pyruvate:ferredoxin (flavodoxin) oxidoreductase. | Acetolactate synthase, small subunit. | 0.963 |