node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OJG78650.1 | OJG85276.1 | RV13_GL003560 | RV13_GL001078 | Histidinol phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | Threonine-phosphate decarboxylase. | 0.591 |
OJG78650.1 | hisB | RV13_GL003560 | RV13_GL003178 | Histidinol phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | Hypothetical protein. | 0.880 |
OJG78650.1 | hisC | RV13_GL003560 | RV13_GL003177 | Histidinol phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | Histidinol-phosphate transaminase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.962 |
OJG78650.1 | hisD | RV13_GL003560 | RV13_GL003176 | Histidinol phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.975 |
OJG78650.1 | hisG | RV13_GL003560 | RV13_GL003175 | Histidinol phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.412 |
OJG78650.1 | hisH | RV13_GL003560 | RV13_GL003179 | Histidinol phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.671 |
OJG78650.1 | hisI | RV13_GL003560 | RV13_GL003182 | Histidinol phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | phosphoribosyl-ATP diphosphatase; In the N-terminal section; belongs to the PRA-CH family. | 0.885 |
OJG85276.1 | OJG78650.1 | RV13_GL001078 | RV13_GL003560 | Threonine-phosphate decarboxylase. | Histidinol phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | 0.591 |
OJG85276.1 | OJG88108.1 | RV13_GL001078 | RV13_GL003181 | Threonine-phosphate decarboxylase. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.921 |
OJG85276.1 | OJG88110.1 | RV13_GL001078 | RV13_GL003183 | Threonine-phosphate decarboxylase. | HisJ family histidinol phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | 0.596 |
OJG85276.1 | hisA | RV13_GL001078 | RV13_GL003180 | Threonine-phosphate decarboxylase. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase. | 0.832 |
OJG85276.1 | hisB | RV13_GL001078 | RV13_GL003178 | Threonine-phosphate decarboxylase. | Hypothetical protein. | 0.974 |
OJG85276.1 | hisD | RV13_GL001078 | RV13_GL003176 | Threonine-phosphate decarboxylase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.944 |
OJG85276.1 | hisG | RV13_GL001078 | RV13_GL003175 | Threonine-phosphate decarboxylase. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.999 |
OJG85276.1 | hisH | RV13_GL001078 | RV13_GL003179 | Threonine-phosphate decarboxylase. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.925 |
OJG85276.1 | hisI | RV13_GL001078 | RV13_GL003182 | Threonine-phosphate decarboxylase. | phosphoribosyl-ATP diphosphatase; In the N-terminal section; belongs to the PRA-CH family. | 0.999 |
OJG88108.1 | OJG85276.1 | RV13_GL003181 | RV13_GL001078 | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | Threonine-phosphate decarboxylase. | 0.921 |
OJG88108.1 | OJG88110.1 | RV13_GL003181 | RV13_GL003183 | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | HisJ family histidinol phosphate phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. | 0.879 |
OJG88108.1 | hisA | RV13_GL003181 | RV13_GL003180 | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase. | 0.999 |
OJG88108.1 | hisB | RV13_GL003181 | RV13_GL003178 | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | Hypothetical protein. | 0.999 |