| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABI_04940 | ABI_07980 | ABI_04940 | ABI_07980 | [C] COG0281 Malic enzyme. | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.913 |
| ABI_04940 | ABI_30370 | ABI_04940 | ABI_30370 | [C] COG0281 Malic enzyme. | Aminotransferase class-V family protein; PRIAM ID: PRI001274; [E] COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | 0.860 |
| ABI_04940 | ABI_35640 | ABI_04940 | ABI_35640 | [C] COG0281 Malic enzyme. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.992 |
| ABI_04940 | ABI_39180 | ABI_04940 | ABI_39180 | [C] COG0281 Malic enzyme. | Amino acid kinase family protein; PRIAM ID: PRI000230; [E] COG0527 Aspartokinases. | 0.720 |
| ABI_04940 | glyA | ABI_04940 | ABI_34790 | [C] COG0281 Malic enzyme. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.671 |
| ABI_07980 | ABI_04940 | ABI_07980 | ABI_04940 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | [C] COG0281 Malic enzyme. | 0.913 |
| ABI_07980 | ABI_23800 | ABI_07980 | ABI_23800 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Low specificity L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.434 |
| ABI_07980 | ABI_30370 | ABI_07980 | ABI_30370 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Aminotransferase class-V family protein; PRIAM ID: PRI001274; [E] COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | 0.936 |
| ABI_07980 | ABI_31760 | ABI_07980 | ABI_31760 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | PRIAM ID: PRI002600; [E] COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain. | 0.545 |
| ABI_07980 | ABI_35640 | ABI_07980 | ABI_35640 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.899 |
| ABI_07980 | ABI_39180 | ABI_07980 | ABI_39180 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Amino acid kinase family protein; PRIAM ID: PRI000230; [E] COG0527 Aspartokinases. | 0.979 |
| ABI_07980 | glyA | ABI_07980 | ABI_34790 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.910 |
| ABI_23800 | ABI_07980 | ABI_23800 | ABI_07980 | Low specificity L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.434 |
| ABI_23800 | ABI_30370 | ABI_23800 | ABI_30370 | Low specificity L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | Aminotransferase class-V family protein; PRIAM ID: PRI001274; [E] COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | 0.842 |
| ABI_23800 | ABI_31760 | ABI_23800 | ABI_31760 | Low specificity L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | PRIAM ID: PRI002600; [E] COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain. | 0.863 |
| ABI_23800 | ABI_39180 | ABI_23800 | ABI_39180 | Low specificity L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | Amino acid kinase family protein; PRIAM ID: PRI000230; [E] COG0527 Aspartokinases. | 0.527 |
| ABI_23800 | glyA | ABI_23800 | ABI_34790 | Low specificity L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.895 |
| ABI_30370 | ABI_04940 | ABI_30370 | ABI_04940 | Aminotransferase class-V family protein; PRIAM ID: PRI001274; [E] COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | [C] COG0281 Malic enzyme. | 0.860 |
| ABI_30370 | ABI_07980 | ABI_30370 | ABI_07980 | Aminotransferase class-V family protein; PRIAM ID: PRI001274; [E] COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.936 |
| ABI_30370 | ABI_23800 | ABI_30370 | ABI_23800 | Aminotransferase class-V family protein; PRIAM ID: PRI001274; [E] COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | Low specificity L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.842 |
