STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL004916AAEL004916-PA. (571 aa)    
Predicted Functional Partners:
AAEL012539
Heparan sulphate n-deacetylase/n-sulfotransferase.
   
 0.959
AAEL003346
AAEL003346-PA.
   
 
 0.666
AAEL001458
Heparan sulphate sulfotransferase.
      
 0.589
AAEL000433
AAEL000433-PA; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
 0.587
AAEL013969
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
    
 0.571
AAEL000491
Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
    
 
 0.543
AAEL000493
Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
    
 
 0.543
AAEL007895
AAEL007895-PA.
      
 0.538
Papst2
Adenosine 3'-phospho 5'-phosphosulfate transporter 2; Mediates the transport of adenosine 3'-phospho 5'- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Essential for viability. Involved in glycosaminoglycan synthesis and the subsequent signaling. May be involved in hh and dpp signaling by controlling the sulfation of heparan sulfate (HS) (By similarity). Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
      
 0.538
AAEL000483
AAEL000483-PA; Belongs to the glycosyltransferase 47 family.
      
 0.538
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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