STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFCDefensin-C; Antibacterial peptide mostly active against Gram-positive bacteria; Belongs to the invertebrate defensin family. Type 1 subfamily. (99 aa)    
Predicted Functional Partners:
REL1
Dorsal isoform 1-A.
     
 0.957
REL1B
AAEL006930-PA.
     
 0.910
DEFA
Defensin-A; Antibacterial peptide mostly active against Gram-positive bacteria. Has activity against the bacteria Gram-negative E.cloacae beta12. Belongs to the invertebrate defensin family. Type 1 subfamily.
     
0.900
IMD
AAEL010083-PA.
      
 0.734
REL2
AAEL007624-PA.
      
 0.523
AAEL006874
Prophenoloxidase.
      
 0.497
AAEL006877
Prophenoloxidase.
      
 0.497
DPT1
AAEL004833-PA.
   
  
 0.496
PPO9
Prophenoloxidase.
      
 0.495
PPO2
Prophenoloxidase.
      
 0.495
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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