STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL003926Translation factor GUF1 homolog, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily. (656 aa)    
Predicted Functional Partners:
AAEL004034
AAEL004034-PA.
   
 
 0.979
RpL5
60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]
   
 
 0.979
AAEL013116
AAEL013116-PA.
   
 
 0.978
AAEL012944
60S ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family.
   
 
 0.978
AAEL011391
AAEL011391-PA.
  
 
 0.978
AAEL003397
39S mitochondrial ribosomal protein L17.
   
 
 0.978
J9HFW1_AEDAE
40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
   
 
 0.977
AAEL013964
60S ribosomal protein L20, putative; Belongs to the bacterial ribosomal protein bL20 family.
  
 
 0.977
AAEL009151
40S ribosomal protein S15/S22; Belongs to the universal ribosomal protein uS8 family.
   
 
 0.977
RpL23-A
60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.
   
 
 0.977
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.