USP protein (Aedes aegypti) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Experiments

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[Homology]

Score

USP

AAEL000395-PA. (484 aa)

Predicted Functional Partners:

EcR

0.999

AAEL002382

0.994

AAEL010715

0.971

AAEL010719

0.939

AAEL007402

0.918

HR96

0.808

J9HEY8_AEDAE

0.773

AAEL005997

0.679

e75B

0.658

AAEL013270

0.633

Your Current Organism:

Aedes aegypti

NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAEL002382	AAEL007402	Q17IC6	Q172G3	AAEL002382-PA.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).	0.749
AAEL002382	AAEL010715	Q17IC6	Q16S41	AAEL002382-PA.	AAEL010715-PA.	0.928
AAEL002382	AAEL010719	Q17IC6	Q16S38	AAEL002382-PA.	Ecdysone receptor A isoform, putative.	0.924
AAEL002382	EcR	Q17IC6	P49880	AAEL002382-PA.	Ecdysone receptor; Receptor for ecdysone. Binds to ecdysone response elements (ECRES); Belongs to the nuclear hormone receptor family. NR1 subfamily.	0.949
AAEL002382	HR96	Q17IC6	Q173A3	AAEL002382-PA.	Hormone receptor-like in 96.	0.860
AAEL002382	J9HEY8_AEDAE	Q17IC6	J9HEY8	AAEL002382-PA.	AAEL017391-PA.	0.918
AAEL002382	USP	Q17IC6	Q0IGE0	AAEL002382-PA.	AAEL000395-PA.	0.994
AAEL002382	e75B	Q17IC6	Q0JRL1	AAEL002382-PA.	Ecdysone-induced protein 75B.	0.956
AAEL005997	USP	Q177Y4	Q0IGE0	AAEL005997-PA; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	AAEL000395-PA.	0.679
AAEL005997	e75B	Q177Y4	Q0JRL1	AAEL005997-PA; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.	Ecdysone-induced protein 75B.	0.589
AAEL007402	AAEL002382	Q172G3	Q17IC6	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).	AAEL002382-PA.	0.749
AAEL007402	AAEL010715	Q172G3	Q16S41	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).	AAEL010715-PA.	0.685
AAEL007402	AAEL010719	Q172G3	Q16S38	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).	Ecdysone receptor A isoform, putative.	0.685
AAEL007402	AAEL013270	Q172G3	Q0IE91	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).	Expressed protein (AHR38).	0.579
AAEL007402	EcR	Q172G3	P49880	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).	Ecdysone receptor; Receptor for ecdysone. Binds to ecdysone response elements (ECRES); Belongs to the nuclear hormone receptor family. NR1 subfamily.	0.685
AAEL007402	HR96	Q172G3	Q173A3	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).	Hormone receptor-like in 96.	0.669
AAEL007402	J9HEY8_AEDAE	Q172G3	J9HEY8	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).	AAEL017391-PA.	0.761
AAEL007402	USP	Q172G3	Q0IGE0	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).	AAEL000395-PA.	0.918
AAEL007402	e75B	Q172G3	Q0JRL1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).	Ecdysone-induced protein 75B.	0.827
AAEL010715	AAEL002382	Q16S41	Q17IC6	AAEL010715-PA.	AAEL002382-PA.	0.928