STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL013970Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (320 aa)    
Predicted Functional Partners:
AAEL004734
UBX domain-containing protein 7.
     
 0.912
AAEL004691
SCF ubiquitin ligase Rbx1 component.
    
 0.882
AAEL000679
AAEL000679-PA.
    
 0.791
AAEL012011
AAEL012011-PA; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.772
AAEL009026
Ubiquitin-conjugating enzyme m; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.772
AAEL008008
AAEL008008-PA; Belongs to the cullin family.
   
 0.728
AAEL013530
AAEL013530-PA; Belongs to the cullin family.
   
 0.728
AAEL801225_b
AAEL006291-PA; Belongs to the cullin family.
   
 0.728
AAEL003466
AAEL003466-PA; Belongs to the cullin family.
    
 0.710
AAEL012306
AAEL012306-PA.
    
 0.704
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.