STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL013431Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (384 aa)    
Predicted Functional Partners:
AAEL005422
Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.978
AAEL009831
Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.
   
 0.936
AAEL008418
Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.
   
 0.936
AAEL007033
Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.
   
 0.936
AAEL005289
AAEL005289-PA; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
    
 0.917
J9HTY0_AEDAE
AAEL017524-PA.
   
 
 0.906
AAEL005714
Prolyl 4-hydroxylase alpha subunit 1.
   
 
 0.906
AAEL007038
AAEL007038-PA.
   
 
 0.906
AAEL006975
Leucine aminopeptidase.
     
  0.900
AAEL002457
AAEL002457-PA.
    
 0.900
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.