STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIWI5AAEL013233-PA; Belongs to the argonaute family. (883 aa)    
Predicted Functional Partners:
AAEL007841
AAEL007841-PA.
   
 0.674
spn-E
Probable ATP-dependent RNA helicase spindle-E; Probable ATP-binding RNA helicase which plays a central role during gametogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons (By similarity).
   
 0.671
AAEL009248
AAEL009248-PA.
   
 0.639
AAEL009987
AAEL009987-PA.
   
 0.632
AAEL008101
AAEL008101-PA.
   
 0.609
AAEL002036
AAEL002036-PA.
   
 0.605
AAEL012437
AAEL012437-PA.
   
 0.528
AAEL011385
AAEL011385-PA.
   
 
 0.519
AAEL004978
Vasa-like protein; Belongs to the DEAD box helicase family.
   
 0.517
AAEL001939
AAEL001939-PA.
   
 0.476
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.