STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL011117Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (431 aa)    
Predicted Functional Partners:
AAEL009416
AAEL009416-PA.
    
 0.997
AAEL001717
AAEL001717-PA.
    
 0.997
AAEL009882
Retinoblastoma-binding protein 4 (rbbp4).
   
 0.937
AAEL002084
Suppressor of defective silencing.
    
 0.909
AAEL003539
AAEL003539-PA.
   
 0.896
AAEL001126
AAEL001126-PB.
    
 0.865
AAEL002772
AAEL002772-PA.
   
 0.863
AAEL008611
AAEL008611-PA.
    
 0.857
AAEL011415
Probable lysine-specific histone demethylase 1; Probable histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3.
   
 0.844
AAEL003650
Inhibitor of growth protein.
    
 0.835
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.