STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL010966Ubiquitin carboxyl-terminal hydrolase. (326 aa)    
Predicted Functional Partners:
AAEL000568
26S proteasome non-ATPase regulatory subunit.
   
 0.972
AAEL002789
26S proteasome regulatory complex subunit RPN12/PSMD8.
   
 0.943
AAEL012419
26S proteasome subunit S9.
   
 0.937
AAEL000270
26S proteasome regulatory subunit 7, psd7.
   
 0.936
AAEL006315
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
   
 0.932
AAEL002401
Proteasome subunit beta.
   
 0.931
AAEL012943
26S protease regulatory subunit; Belongs to the AAA ATPase family.
   
 0.927
AAEL012095
26S proteasome regulatory chain 4; Belongs to the AAA ATPase family.
   
 0.925
AAEL010048
AAEL010048-PA.
   
 0.922
AAEL014915
AAEL014915-PA.
   
 0.917
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.