STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL010238Phosphatidylinositol-4-phosphate 5-kinase type i. (517 aa)    
Predicted Functional Partners:
AAEL009294
Phosphatidylinositol 4-kinase; Belongs to the PI3/PI4-kinase family.
   
 0.960
AAEL000194
AAEL000194-PA; Belongs to the PI3/PI4-kinase family.
   
 0.951
AAEL009380
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
    
 0.936
AAEL007660
AAEL007660-PA.
    
 0.927
AAEL002903
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
     
 0.927
AAEL004379
AAEL004379-PA.
     
 0.922
AAEL011417
AAEL011417-PA.
    
 0.917
AAEL004431
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
     
 0.913
AAEL001664
AAEL001664-PA.
   
 0.912
AAEL010124
Phosphoinositide phospholipase C.
     
 0.911
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.