STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL008847Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (333 aa)    
Predicted Functional Partners:
AAEL014596
AAEL014596-PA; Belongs to the membrane-bound acyltransferase family.
    
 0.948
AAEL000104
AAEL000104-PA.
    
 0.931
AAEL009806
Low-density lipoprotein receptor (ldl).
    
 0.930
AAEL011386
AAEL011386-PB.
    
 0.917
GPRFZ1
GPCR Frizzled/Smoothened Family; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.787
GPRFZ5
AAEL009986-PA; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.787
GPRFZ4
AAEL008322-PA; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.787
GPRFZ2
AAEL006778-PA; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.787
AAEL007842
AAEL007842-PA.
    
 0.653
AAEL006708
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 
 0.595
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.