STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL0052013-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (464 aa)    
Predicted Functional Partners:
AAEL009311
3-hydroxy-3-methylglutaryl coenzyme A reductase.
  
 
 0.999
AAEL006912
Acetyl-coa acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.998
AAEL006634
AAEL006634-PA; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.998
AAEL002296
AAEL002296-PA; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.998
AAEL010697
AAEL010697-PA; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.997
AAEL002065
AAEL002065-PA.
     
 0.992
AAEL009501
AAEL009501-PA; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.953
AAEL006435
Mevalonate kinase.
  
 
 0.945
AAEL011137
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 
 0.939
AAEL010611
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.910
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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