STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL005059Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (193 aa)    
Predicted Functional Partners:
AAEL008740
AAEL008740-PA.
   
 0.907
AAEL001484
Chromosome region maintenance protein 1/exportin.
    
 
 0.613
AAEL009160
AAEL009160-PA; Belongs to the SKP1 family.
    
 
 0.528
AAEL010692
OCP-II protein, putative; Belongs to the SKP1 family.
    
 
 0.528
AAEL010651
AAEL010651-PA; Belongs to the SKP1 family.
    
 
 0.528
J9EAJ5_AEDAE
AAEL009634-PE; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.473
AAEL011193
Steroid dehydrogenase.
   
 0.473
AAEL009634
AAEL009634-PC; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.473
AAEL006496
AAEL006496-PA; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.473
AAEL000830
AAEL000830-PA; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.473
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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