STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL004709AAEL004709-PA. (519 aa)    
Predicted Functional Partners:
J9HEZ7_AEDAE
AAEL017059-PA.
   
 0.764
AAEL009766
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
   
 0.692
AAEL002936
AAEL002936-PA.
    
 0.683
AAEL008366
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 0.679
AAEL008398
AAEL008398-PA.
  
 0.649
AAEL008379
Mitogen-activated protein kinase.
   
 0.620
AAEL006838
AAEL006838-PA.
   
 0.582
AAEL006951
Protein phosphatase; Belongs to the PP2C family.
    
 
 0.560
AAEL014750
Pyruvate dehydrogenase.
    
 
 0.551
AAEL005279
AAEL005279-PA.
  
   0.539
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.