STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL004520Phosphodiesterase. (1087 aa)    
Predicted Functional Partners:
Adk2
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
     
 0.917
AAEL000062
Adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    
 0.913
AAEL012294
Adenylate cyclase type ix; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    
 0.913
AAEL005177
Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
    
 0.913
AAEL006659
AAEL006659-PA.
     
 0.909
AAEL001856
AAEL001856-PA.
     
 0.909
AAEL000629
GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
     
 0.909
AAEL000258
5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family.
     
 0.909
AAEL001102
Adenosine kinase.
     
 0.909
AAEL015410
AAEL015410-PA.
     
 0.907
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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