STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL004235Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (718 aa)    
Predicted Functional Partners:
AAEL014084
AAEL014084-PA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
0.882
AAEL008890
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
0.861
AAEL013390
AAEL013390-PA.
   
 0.843
AAEL011596
Mitotic checkpoint serine/threonine-protein kinase bub1 and bubr1.
   
 0.829
AAEL008116
AAEL008116-PA.
   
 0.779
AAEL002714
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
0.766
AAEL003865
AAEL003865-PA.
   
  
 0.762
AAEL008316
AAEL008316-PA.
   
 0.756
SAK
Serine/threonine-protein kinase PLK4; Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the mother centriole cylinder, leading to the recruitment of centriole biogenesis proteins. When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase (By similarity).
   
 0.754
AAEL008863
AAEL008863-PA.
   
 
 0.735
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.