STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL003157Protein SMG8; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Probable component of kinase complex containing SMG1 and recruited to stalled ribosomes (By similarity). (916 aa)    
Predicted Functional Partners:
AAEL004420
AAEL004420-PB.
    
 0.997
AAEL010940
AAEL010940-PA.
   
 0.954
AAEL010928
AAEL010928-PA; Belongs to the PI3/PI4-kinase family.
   
 0.954
AAEL004986
AAEL004986-PA.
     
 0.828
AAEL001187
AAEL001187-PA.
   
 
 0.780
AAEL000693
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
   
 0.738
AAEL008123
AAEL008123-PA; Belongs to the PI3/PI4-kinase family.
   
 0.733
AAEL005525
AAEL005525-PA.
     
 0.684
AAEL005526
AAEL005526-PA.
     
 0.684
AAEL010598
AAEL010598-PA.
   
  
 0.640
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.