STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL002948AAEL002948-PA. (215 aa)    
Predicted Functional Partners:
AAEL004071
AAEL004071-PA; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
    
 0.997
AAEL010743
Cysteine desulfurylase.
   
 0.994
AAEL005415
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
    
 0.990
AAEL005928
AAEL005928-PA; Belongs to the complex I LYR family.
    
 0.989
AAEL008136
Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.
     
 0.939
AAEL006564
AAEL006564-PA; Belongs to the mitochondrial carrier (TC 2.A.29) family.
    
 
 0.931
AAEL002148
AAEL002148-PA.
   
  
 0.776
AAEL011584
AAEL011584-PA; Belongs to the chaperonin (HSP60) family.
    
 0.727
AAEL004438
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
     
 0.719
AAEL006428
AAEL006428-PA.
     
 0.705
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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