STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL002221AAEL002221-PA. (185 aa)    
Predicted Functional Partners:
AAEL005186
AAEL005186-PA.
    
 0.971
AAEL005980
AAEL005980-PA.
   
 
 0.747
AAEL003914
Calcium/calmodulin-dependent serine protein kinase membrane-associated guanylate kinase (cask); Belongs to the MAGUK family.
    
 0.729
AAEL003918
Calcium-dependent protein kinase.
    
 0.729
AAEL011653
AAEL011653-PA; Belongs to the AAA ATPase family.
      
 0.640
AAEL008398
AAEL008398-PA.
    
 0.620
AAEL000999
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
      
 0.614
AAEL014639
Ubiquitin conjugating enzyme, putative; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.596
AAEL000231
AAEL000231-PA.
    
 
 0.596
J9HG26_AEDAE
AAEL017135-PA.
    
 
 0.577
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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