STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAEL002172Tyrosine-protein kinase. (959 aa)    
Predicted Functional Partners:
AAEL002137
Transcriptional adapter.
 
      0.715
AAEL003750
AAEL003750-PA.
    
 0.650
AAEL001475
AAEL001475-PA.
    
 0.637
AAEL013786
Growth factor receptor-bound protein.
    
 0.553
AAEL002554
AAEL002554-PB.
    
 0.528
AAEL004431
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.509
AAEL013596
Phosphatidylinositol 3-kinase regulatory subunit.
    
 0.505
AAEL000129
AAEL000129-PA.
    
 0.454
AAEL000145
AAEL000145-PA.
    
 0.454
AAEL008739
AAEL008739-PA.
   
 0.452
Your Current Organism:
Aedes aegypti
NCBI taxonomy Id: 7159
Other names: A. aegypti, Stegomyia aegypti, yellow fever mosquito
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.