STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RP20_CCG002102Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requ [...] (159 aa)    
Predicted Functional Partners:
RP20_CCG027746
MIF4G_like_2 domain-containing protein.
   
 0.999
RP20_CCG018364
Small nuclear ribonucleoprotein G.
   
 0.994
RP20_CCG018337
Uncharacterized protein.
    
 0.993
RP20_CCG009770
RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
   
 0.991
RP20_CCG001573
Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.
   
 0.986
RP20_CCG000131
U1 small nuclear ribonucleoprotein C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA; Belongs to the U1 small nuclear ribonucleoprotein C family.
    
 
 0.985
RP20_CCG004231
Uncharacterized protein.
   
 
 0.985
RP20_CCG019047
Uncharacterized protein.
    
 
 0.982
RP20_CCG023599
CPSF_A domain-containing protein.
    
 0.981
RP20_CCG000183
Putative spliceosomal protein snrnp-u1a/u2b.
   
 
 0.980
Your Current Organism:
Aedes albopictus
NCBI taxonomy Id: 7160
Other names: A. albopictus, Asian tiger mosquito, Stegomyia albopicta, forest day mosquito
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.