STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RP20_CCG026259Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)    
Predicted Functional Partners:
RP20_CCG002710
Rep_fac_C domain-containing protein.
  
 0.999
RP20_CCG011328
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 0.999
RP20_CCG006220
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
 0.998
RP20_CCG017771
AAA domain-containing protein.
  
 0.998
RP20_CCG021045
DNA ligase.
   
 0.998
RP20_CCG012623
Uncharacterized protein.
   
 0.997
RP20_CCG023468
Uncharacterized protein.
  
 0.997
RP20_CCG000408
zf_UBZ domain-containing protein.
   
 0.996
RP20_CCG025418
AAA domain-containing protein.
  
 0.996
RP20_CCG000490
Uncharacterized protein.
  
 0.993
Your Current Organism:
Aedes albopictus
NCBI taxonomy Id: 7160
Other names: A. albopictus, Asian tiger mosquito, Stegomyia albopicta, forest day mosquito
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.