STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RP20_CCG002118Uncharacterized protein. (1369 aa)    
Predicted Functional Partners:
RP20_CCG007120
Putative ubiquitin/60s ribosomal protein l40 fusion.
   
0.999
RP20_CCG001575
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
0.998
RP20_CCG003686
UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family.
   
 0.996
RP20_CCG003326
Ubiquitin conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.995
RP20_CCG005393
Uncharacterized protein.
   
 0.994
RP20_CCG007534
Putative ubiquitin conjugating enzyme 4; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.993
RP20_CCG018188
Putative 26s proteasome regulatory complex subunit rpn11.
   
 0.993
RP20_CCG000782
Putative 26s proteasome regulatory complex subunit.
   
 0.992
RP20_CCG023815
PCI domain-containing protein.
   
 0.991
RP20_CCG024495
Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.
    
 0.989
Your Current Organism:
Aedes albopictus
NCBI taxonomy Id: 7160
Other names: A. albopictus, Asian tiger mosquito, Stegomyia albopicta, forest day mosquito
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.