STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RP20_CCG002861Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (188 aa)    
Predicted Functional Partners:
RP20_CCG008250
Pribosyltran domain-containing protein.
  
 0.981
RP20_CCG003266
NDK domain-containing protein.
  
 
 0.968
RP20_CCG007417
Nucleoside diphosphate kinase.
  
 
 0.967
RP20_CCG008228
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
   
 0.967
RP20_CCG021110
Nucleoside diphosphate kinase.
  
 0.964
RP20_CCG010960
dUTPase domain-containing protein.
  
 0.964
RP20_CCG006791
Uncharacterized protein.
  
 
 0.962
RP20_CCG003584
Guanylate kinase-like domain-containing protein.
  
 
 0.953
RP20_CCG017663
GTP_cyclohydroI domain-containing protein.
  
 
 0.952
RP20_CCG020706
MGS domain-containing protein.
     
 0.949
Your Current Organism:
Aedes albopictus
NCBI taxonomy Id: 7160
Other names: A. albopictus, Asian tiger mosquito, Stegomyia albopicta, forest day mosquito
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.