STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RP20_CCG009896DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (564 aa)    
Predicted Functional Partners:
RP20_CCG015694
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
  
 0.999
RP20_CCG013353
DNA polymerase.
   
 0.995
RP20_CCG013722
DNA polymerase.
   
 0.995
RP20_CCG014873
DNA_pol_E_B domain-containing protein.
   
 0.989
RP20_CCG021295
DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
   
 0.989
RP20_CCG026259
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 
 0.980
RP20_CCG009141
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
   
 0.980
RP20_CCG023468
Uncharacterized protein.
   
 0.978
RP20_CCG009140
DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.
   
 0.972
RP20_CCG014280
Uncharacterized protein.
   
 
 0.969
Your Current Organism:
Aedes albopictus
NCBI taxonomy Id: 7160
Other names: A. albopictus, Asian tiger mosquito, Stegomyia albopicta, forest day mosquito
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.