STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0NCE0_ANOGAAGAP000368-PA; Belongs to the PI3/PI4-kinase family. (3308 aa)    
Predicted Functional Partners:
Q7PWZ4_ANOGA
Regulator of nonsense transcripts 1.
    
 0.998
F5HLG8_ANOGA
AGAP004504-PB.
    
 
 0.989
Q7Q9U9_ANOGA
AGAP005036-PA.
    
 0.987
Q7Q0T1_ANOGA
AGAP010179-PA.
   
 0.986
Q7QF75_ANOGA
AGAP000337-PA.
   
 
 0.981
Q7PLZ0_ANOGA
Eukaryotic peptide chain release factor subunit.
    
 
 0.979
Q7PQQ2_ANOGA
ATP-dependent RNA helicase; Belongs to the DEAD box helicase family.
   
 
 0.971
Q7Q5L6_ANOGA
RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
    
 
 0.961
Cbp20
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requ [...]
    
 
 0.961
Q7PVE0_ANOGA
AGAP009310-PA.
    
 
 0.952
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.