STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0NEZ8_ANOGAAGAP000915-PA. (309 aa)    
Predicted Functional Partners:
Q5TX48_ANOGA
GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
   
 0.970
Q7QD70_ANOGA
E3 SUMO-protein ligase RanBP2.
   
 0.773
A7UUK5_ANOGA
Ran GTPase-activating protein 1.
   
 
 0.766
Q7PCX0_ANOGA
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
  0.698
PrBP
Probable cGMP 3',5'-cyclic phosphodiesterase subunit delta; Belongs to the PDE6D/unc-119 family.
    
 
 0.690
Q7PUE1_ANOGA
Importin subunit alpha; Belongs to the importin alpha family.
   
 
 0.667
Q7Q1H0_ANOGA
Importin subunit alpha; Belongs to the importin alpha family.
   
 
 0.667
Q7Q7B4_ANOGA
Importin subunit alpha; Belongs to the importin alpha family.
   
 
 0.667
Q7PQ55_ANOGA
Ran-binding protein 3.
    
 
 0.619
Q7PMB7_ANOGA
AGAP009929-PA.
    
 
 0.590
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.