STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0NGZ6_ANOGAAGAP001683-PA; Belongs to the MAGUK family. (918 aa)    
Predicted Functional Partners:
F5HJI6_ANOGA
AGAP000449-PB.
   
 0.999
Q7Q3G7_ANOGA
AGAP007865-PA.
    
 0.999
URM1_ANOGA
Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress spec [...]
    
 0.999
Q7QFF3_ANOGA
AGAP000452-PA.
   
 0.999
Q7QE59_ANOGA
AGAP000810-PA.
    
0.993
Q7PSM9_ANOGA
AGAP004066-PA.
    
 0.980
F5HJN1_ANOGA
Disks large protein 1.
   
0.976
Q7PKP8_ANOGA
AGAP001469-PA.
    
 0.974
Q7QIZ0_ANOGA
AGAP007137-PA.
    
 0.974
Q7PW85_ANOGA
Lipopolysaccharide-induced TNF-alpha transcription factor (LITAF-like 3).
   
 0.971
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.