T23O_ANOGA protein (Anopheles gambiae) - STRING interaction network

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T23O_ANOGA

Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (392 aa)

Predicted Functional Partners:

Q7QKH2_ANOGA

0.990

Q7Q665_ANOGA

0.949

Q7PW49_ANOGA

0.901

kh

0.901

Q7QCC9_ANOGA

0.877

Q7QF69_ANOGA

0.854

Q7QHE7_ANOGA

0.793

F5HIW7_ANOGA

0.720

Q7Q7P0_ANOGA

0.720

Q7QA02_ANOGA

0.720

Your Current Organism:

Anopheles gambiae

NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F5HIW7_ANOGA	T23O_ANOGA	F5HIW7	O77457	AGAP003887-PB.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.720
Q7PW49_ANOGA	Q7Q665_ANOGA	Q7PW49	Q7Q665	AGAP009091-PA.	AGAP006020-PA.	0.930
Q7PW49_ANOGA	Q7QF69_ANOGA	Q7PW49	Q7QF69	AGAP009091-PA.	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.	0.910
Q7PW49_ANOGA	Q7QKH2_ANOGA	Q7PW49	Q7QKH2	AGAP009091-PA.	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.	0.907
Q7PW49_ANOGA	T23O_ANOGA	Q7PW49	O77457	AGAP009091-PA.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.901
Q7Q665_ANOGA	Q7PW49_ANOGA	Q7Q665	Q7PW49	AGAP006020-PA.	AGAP009091-PA.	0.930
Q7Q665_ANOGA	T23O_ANOGA	Q7Q665	O77457	AGAP006020-PA.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.949
Q7Q665_ANOGA	kh	Q7Q665	Q7Q6A7	AGAP006020-PA.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.528
Q7Q7P0_ANOGA	T23O_ANOGA	Q7Q7P0	O77457	Phosphotransferase LOC123688.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.720
Q7Q7P0_ANOGA	kh	Q7Q7P0	Q7Q6A7	Phosphotransferase LOC123688.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.672
Q7QA02_ANOGA	T23O_ANOGA	Q7QA02	O77457	AGAP004500-PA.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.720
Q7QCC9_ANOGA	T23O_ANOGA	Q7QCC9	O77457	Hormone-sensitive lipase.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.877
Q7QCC9_ANOGA	kh	Q7QCC9	Q7Q6A7	Hormone-sensitive lipase.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.640
Q7QF69_ANOGA	Q7PW49_ANOGA	Q7QF69	Q7PW49	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.	AGAP009091-PA.	0.910
Q7QF69_ANOGA	T23O_ANOGA	Q7QF69	O77457	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.854
Q7QF69_ANOGA	kh	Q7QF69	Q7Q6A7	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.587
Q7QHE7_ANOGA	Q7QKH2_ANOGA	Q7QHE7	Q7QKH2	AGAP011158-PA.	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.	0.948
Q7QHE7_ANOGA	T23O_ANOGA	Q7QHE7	O77457	AGAP011158-PA.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.793
Q7QHE7_ANOGA	kh	Q7QHE7	Q7Q6A7	AGAP011158-PA.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.976
Q7QKH2_ANOGA	Q7PW49_ANOGA	Q7QKH2	Q7PW49	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.	AGAP009091-PA.	0.907

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