STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASNA_ANOGAATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] (337 aa)    
Predicted Functional Partners:
Q7QH65_ANOGA
AGAP004056-PA.
    
 0.994
Q7QER9_ANOGA
Golgi to ER traffic protein 4 homolog.
    
 0.993
Q7PRQ2_ANOGA
UV excision repair protein RAD23.
   
 0.946
Q7PVI6_ANOGA
AGAP009266-PA.
    
 0.932
Q7QDC4_ANOGA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha.
   
 0.871
Q7PPP0_ANOGA
AGAP008756-PA.
   
 0.773
Q7PVG5_ANOGA
AGAP009284-PA.
    
 0.765
Q7PVG7_ANOGA
AGAP009283-PA.
    
 0.765
A7UTZ2_ANOGA
AGAP005963-PA.
    
 0.705
Q7QC06_ANOGA
Ubiquitin-like 4A.
    
 0.697
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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